clean room

clean room

What is a clean room?

If you are trying to create a clean room for your laboratory, this article is for you.

In general, clean rooms follow certain rules to help pharmaceutical manufacturers control environmental contamination, temperature, and sometimes humidity.

Clean rooms are usually used to protect pharmaceutical products or processes from human and environmental contamination.
So, if you think you need a clean space to conduct your experiments, you can definitely use this resource for your research.
If you know human and environmental pollution well and know the principles of controlling it, you can think much better about the process of creating a clean room.

  • furniture
    • Walls, floors and ceilings
    • Color and cover
    • Building materials (sawdust, plaster, etc.)
    • Air filter residue
    • Room air and vapors
    • Pores and holes
  • tools
    • Abrasive tools
    • Tools that produce greenhouse gases
    • Vibration tools
    • Cleaning tools such as brooms
  • Produced materials
    • Silicone strips
    • Quartz sheets
    • The remains of the clean room
    • Aluminum particles
  • Human beings
    • Oily skin
    • Cosmetics and perfumes
    • Clothing remnants such as fibers, cloth, wool, etc.
    • wool
  • Liquids and gases
    • Particles floating in the air
    • Bacteria, organic matter and moisture
    • Floor coverings and coverings
    • Chemical detergents
    • plastics
    • deionized water

cleanse: Main for pollution control

 

  • To clean a clean room, first of all, have a checklist and program.
  • Define what clean means and know how it is measured.
  • Specify the materials allowed to be used in the room.
  • Have a specific schedule for cleaning and how often.

Architecture of clean rooms

 

You should know that the more closed the environment is, or the lower the air flow, the more likely contamination is. Because air flow can cause particles to move. Clean rooms are usually designed with several layers of air in the ceiling and walls, in which case the air flow is established uniformly at all points.

 

Levels

 

All surfaces should be smooth and impervious to dirt, moisture and dust, and of course, they should be easy to clean.

 

door

 

All doors must be opened by pushing into the room unless the doors open or close automatically and there is no need to push the door.

 

airflow

 

Ventilation and air flow purification are important and vital to keep a CLEAN ROOM clean. In general, if you want to have a cleaner CLEAN ROOM, you will definitely need a better and more suitable air flow.

 

High efficiency air filter (HEPA)

 

In general, air filters that can filter materials with a size of 0.3 microns to at least 99% are suitable for clean rooms. In addition, be sure to pay attention to the use of additional filters to filter liquids and gases.

 

Work clothes for clean rooms

 

For working in clean rooms, face mask, gloves and head cover are a mandatory standard, which are important in the place of clean materials.

 

CLEAN ROOM personnel

 

Clean room personnel usually carry the highest risk of contamination. Particles in the air and microbes in the human body can increase pollution.

  1. All materials and equipment brought into the clean room must be completely sterilized before entering.
  2. Any material or device that enters the room must be approved in advance and have permission to enter the room. Including gloves, clothes, pliers and even writing tools.
  3. Everything that enters the clean room must be cleaned according to its own standard. (means tools or containers)
  4. If you are not using a tool, do not put it directly on the table or chair and be sure to use a clean and approved cover for this.
  5. Personal items such as jewelry and keys should not be placed inside the room. If anything is left in the pocket, they should never be in the approved clothing in the clean room environment.
  6. If the user or staff of the room is physically ill, they should not enter the room under any circumstances.
  7. When using HEPA filters, use special dryers and never use cloth towels or paper towels.
  8. Any type of cosmetics and perfumes are prohibited and should not be used in the CLEAN ROOM.
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